top of page

PUBLICATIONS

PUBLICATIONS

65. Several papers are in preparation. 

64. Minjae Kim, Yong Namkung, Donghun Hyun, and Sunghoi Hong . Prediction of Stem Cell State Using Cell Image-Based Deep Learning. Advanced Intelligent Systems.17 April 2023. IF: 7.4. DOI: 10.1002/aisy.202300017

63. Wonjin Yun, Kyung-Ah Choi, Insik Hwang,…, Sunghoi Hong and Seungkwon You. OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease. NPJ REGENERATIVE MEDICINE 2022 (JAN), 7(1). IF : 14.404 Co-corresponding author.

62. Jeong H et al. GCC2 as a New Early Diagnostic Biomarker for Non-Small Cell Lung Cancer. Cancers 2021(Nov), 13(21), 5482. https://doi.org/10.3390/cancers13215482. IF : 6.639. Corresponding author.
 

61. Jeong H et al. Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines. GENES & GENOMICS. 2021(Sept), 43(9), 995~1001. IF : 1.839. Corresponding author.

60. Ka-Won Kang et al. A Proteomic Approach to Understand the Clinical Significance of Acute Myeloid Leukemia-Derived Extracellular Vesicles Reflecting Essential Characteristics of Leukemia. MOLECULAR & CELLULAR PROTEOMICS. 2021(June), 20, pp~pp IF : 5.911. 
 

59. Jik-Han Jung et al. Dual size-exclusion chromatography for efficient isolation of extracellular vesicles from bone marrow derived human plasma. SCIENTIFIC REPORTS. 2021(Jan), 11:217. IF : 4.13. 
 

58. Hyunku Shin et al. Early-Stage Lung Cancer Diagnosis by Deep Learning-Based Spectroscopic Analysis of Circulating Exosomes. ACS NANO. 2020(May), 14(5). 5435-5444. IF : 15.881.

57. Seung-ick Oh et al. Activation of CXCL12-CXCR4 signalling induces conversion of immortalised embryonic kidney cells into cancer stem-like cells. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY. 2020(Nov), 48(1), 516-529. IF : 5.24. Corresponding author.

56. Choi KA et al. Tissue inhibitor of metalloproteinase proteins inhibit teratoma growth in mice transplanted with pluripotent stem cells. Stem Cells 2020, 38, 516-529. IF : 6.227. Corresponding author.

55. Kyung-Ah Choi, Han-Kyul Park, Insik Hwang, Hyesun Jeong, Hang-Soo Park, Ah-Young Jang, Yong Namkung, Donghun Hyun, Seulbee Lee, Byung Min Yoo, Han-Jin Kwon, Ki-Cheon Seol, Jeong-Ok Kim, Sunghoi Hong. 2019. Tissue inhibitor of metalloproteinase proteins inhibit teratoma growth in mice transplanted with pluripotent stem cells. Stem Cells,  IF : 5.614

54. Insik Hwang, Kyung-Ah Choi, Minjae Kim, Sunghoi Hong. Neural stem cells and the secreted proteins TIMPs ameliorate UVB-induced skin photodamage. BBRC, IF : 2.705

53. Hyunku Shin, Hyesun Jeong,  Jaena Park,  Sunghoi, Yeonho Choi. 2018. Correlation between Cancerous Exosomes and Protein Markers Based on Surface-Enhanced Raman Spectroscopy (SERS) and Principal Component Analysis (PCA). ACS Sens, IF : 5.711

52. Hang-Soo Park, Hyosung Kwon, Jewon Yu, Jae-Yong Park, Kyung-Ah Choi, Yeonho Choi, Sunghoi Hong. 2018. Precise nanoinjection delivery of plasmid DNA into a single fibroblast for direct conversion of astrocyte. Artificial Cells, Nanomedicine, and Biotechnology. IF : 3.026 *Corresponding author.
51. Insik Hwang, Sunghoi Hong, 2017. Neural Stem Cells and Its Derivatives as a New Material for Melanin Inhibition. Int. J. Mol. Sci. IF : 3.226. *Corresponding author.

50. Kyung-Ah Choi, Yeonho Choi, Sunghoi Hong. 2017. Stem cell transplantation for Huntington's diseases. METHODS.IF : 3.802. *Corresponding author.

49. Kyung-Ah Cho, Sunghoi Hong. 2017. Induced neural stem cells as a means of treatment in Huntingtons disease. Expert Opinion on Biological Therapy. IF : 3.684 *Corresponding author.

48. Jaena Park, Miyeon Hwang, ByeongHyeon Choi, Hyesun Jeong, Jik-han Jung, Hyun Koo Kim, Sunghoi Hong, Ji-ho Park, and Yeonho Choi. 2017. Exosome Classification by Pattern Analysis of Surface-Enhanced Raman Spectroscopy Data for Lung Cancer Diagnosis. Analytical chemistry. IF : 6.320

47. Kyung-Ah Choi, Han-Kyul Park, Insik Hwang, Hyesun Jeong, Hang-Soo Park, Han-Jin Kwon, Byung Min Yoo, Jeong-Ok Kim, Ki-Cheon Seol and Sunghoi Hong*. 2016. Neural stem cell inhibits teratoma growth in mice transplanted with pluripotent stem cells. Cell Transplantation. IF : 3.127 *Corresponding author.

46. Ju-Hwang Park, Hang-Soo Park, Yunjung Jin, Sunghoi Hong and Seongman Kang. 2016.  Motor neurons derived from ALS-related miPS cells recapitulate pathological features of ALS. EMM. IF : 5.164

45. Zheng J, Choi KA, Kang PJ, Hyeon S, Kwon S, Moon JH, Hwang I, Kim YI, Kim YS, Yoon BS, Park G, Lee J, Hong S*, You S*. 2016. A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells. Biochem Biophys Res Commun. IF : 2.297 *Co-corresponding author.

44. Insik Hwang , Kyung-Ah Choi, Hang-Soo Park, Hyesun Jeong, Jeong-Ok Kim, Ki-Cheon Seol, Han-Jin Kwon, In-Hyun Park and Sunghoi Hong*. 2016. Neural stem cells restore hair growth throughactivation of the hair follicle niche. Cell Transplantation. 25(8):1439-1451. IF : 3.127 *Corresponding author.
 
43. Insik Hwang , Suk-Chan Hahm, Kyung-Ah Choi, Sung-Ho Park, Hyesun Jeong, Ji-Hye Yea, Junesun Kim and Sunghoi Hong*. 2015 (Sep). Intrathecal Transplantation of Embryonic StemCell-Derived Spinal GABAergic Neural Precursor Cells Attenuates NeuropathicPain in a Spinal Cord Injury Rat Model. Cell Transplantation. 2016;25(3):593-607. IF : 3.127 *Correspondingauthor.
 
42. Hyosung Kwon, Hang-Soo Park, Sunghoi Hong* and Yeonho Choi*. 2015 (July).Spatio-temporallycontrolled transfection by quantitative injection into asingle cell. Biomaterials. IF :8.557. *Co-correspondingauthor.
 
41. A-ram Kang, SiHoon Park, Soyeon Lee, Do-YoungChoi, Kwang Pyo Kim, Hyun Kyu Song, SunghoiHong and Seongman Kang*. 2015 (May). Akey lysineresidue in the AXH domain of ataxin-1 is essential for itsubiquitylation. BBA protein. IF : 2.747.
 
40. Hang-SooPark, Insik Hwang, Kyung-Ah Choi, Hyesun Jeong,Ji-Yun Lee and Sunghoi Hong*. 2015 (Jan). Generationof inducedpluripotent stem cells without genetic defects by small molecules. Biomaterials. IF : 8.557. *Correspondingauthor.
 
39. Hyesun Jeong,Jiwon Sung, Seung-Ick Oh,Seonghoon Jeong, Eui Kwan Koh, SunghoiHong* and Myonggeun Yoon*. 2014 (November).Inhibitionof brain tumor cell proliferation by alternating electric fields. Applied Physics Letters(APL). IF :3.515. *Co-correspondingauthor.
 
38. Seung-Ick Oh, Hang-Soo Park, Insik Hwang, Han-kyul Park and SunghoiHong*. 2014 (June).Efficientreprogramming of mouse fibroblasts to neuronal cells includingdopaminergicneurons. The ScienticWorldJournal. 957848,1-8. IF : 1.73. *Correspondingauthor.
 
37. Kyung-Ah Choi, Insik Hwang, Hang-Soo Park, Seung-Ick Oh, SeongmanKang and Sunghoi Hong*. 2014 (Apr). Stemcelltherapy and cellular engineering for treatment of neuronal dysfunctioninHuntington’s disease. BoitechnologyJournal.9(7)882-894. IF : 3.446. *Correspondingauthor.
 
36. Sunghoi Hong*, Sangmi Chung,Kaka Leung, Insik Hwang, Ji SookMoon, Kwang-Soo Kim*. 2014 (Mar).Functionalroles of Nurr1, Pitx3 and Lmx1a in neurogenesis and phenotypespecification ofdopamine neurons during in vitro differentiation of embryonicstem cells. Stem Cells and Development.23(5):477-487.IF : 4.67. *Co-corresponding author.
 
35.Insik Hwang, Ju-Hwang Park, Hang-SooPark, Kyung-Ah Choi, Ki-Cheon Seol ,Seung-Ick Oh, Seongman Kang andSunghoiHong*. 2013 (Dec). Neural stemcells inhibit melanin productionby activation of Wnt inhibitors. Journal of Dermatological Science.72(3):274-283. IF : 3.52 *Correspondingauthor.
 
34. Ji Sook Moon, Hyun-SeobLee, Jun Mo Kang, Junpil Park,Amanda Leung, Sunghoi Hong, SangmiChung, Kwang-Soo Kim. 2013(Oct).Stem cellgrafting improves both motor and cognition impairments in a geneticmodel ofParkinson’s disease, the Aphakia (ak) mouse . Cell Transplantation. 22:1263-1279. IF : 4.422. 
 
33. Seung-Ick Oh,Chang Kyu Lee, Kyung Jin Cho, Kyung-Ok Lee,Ssang-Goo Cho, and Sunghoi Hong*. 2012 (Dec). Technological Progress inGeneration of InducedPluripotent Stem Cells for Clinical Applications. The Scientic World Journal. 2012:1-10. IF : 1.567. (SCIE) *Corresponding author. (This article was highlighted in“GlobalMedical Discovery” as a key scientic article in Aug 12, 2012)
 
32. Seongman KangandSunghoi Hong*. 2011 (DEC). Prediction of personalized drugs basedon genetic variationsprovided by DNA sequencing technologies. Genes& Genomics. 33:591-603. IF : 0.442(SCIE) *Corresponding author.
 
31. Chang HyunLee, Jung-HyunKim, Hyun Joo Lee, Kilsoo Jeon,HyeJin Lim, Hye yeon, Choi, Eung-Ryoung Lee,Seung Hwa Park, Jae-Yong Park, SunghoiHong, Soonhag Kim, Ssang-GooCho. 2011(Oct). The generation ofiPS cells using non-viral magnetic nanoparticle basedtransfection. Biomaterials. 32:6683-6691.IF : 7.882
 
30. Soyoen Lee,Sunghoi Hong, Sungsu Kim and SeongmanKang. 2011 (May). Ataxin-1 occupiesthe promoter region of E-cadherin in vivoand activates CtBP2-repressedpromoter. Biochimicaet BiophysicaActa-Molecular Cell Research (BBAMCR). 1813:713-722. IF : 4.733 
 
29. Seongman Kang and Sunghoi Hong*. 2010 (December). SUMO-1 interacts with mutant ataxin-1and colocalizes in Purkinjecells of SCA1 transgeneic mice. ArchivesItaliennes de Biologie148:351-363. IF: 1.433  *Corresponding author.
 
28. Sangmi Chung,Amanda Leung, Back-Soo Han, Mi-Yoon Chang,Jung-Il Moon, Chun-Hyung Kim, SunghoiHong, Jan Pruszak, Ole Isacson,and Kwang-Soo Kim. 2009 (December4). Wnt1-lmx1a forms a novel autoregulatory loop andcontrols midbraindopaminergic differentiation synergistically with the SHH-FoxA2pathway. Cell Stem Cell. 5:1-13. IF : 23.563
 
27. Dong-YounHwang, SunghoiHong, Joo-Won Jeong,Sangdun Choi, Hansoo Kim, Jangwoo Kim, and Kwang-SooKim.2009 (September 24). VMAT2 andDAT are molecular targets of Pitx3in the ventral midbrain dopamine neurons. Journalof Neurochemistry. 111:1201-1212.IF: 4.5
 
26. Man Ki Song,Jun Chang, Yeongjin Hong, Sunghoi Hong,and Suhng Wook Kim. 2009 (July 22)Direct Multiplex Reverse Transcription-Nested PCR Detection ofInfluenza VirusesWithout RNA Purification. JournalMicrobiology and Biotechnology.19(11):1470-1474. IF : 2.1 (SCIE)
 
25. Seongman Kangand  Sunghoi Hong*. 2009 (June30).Molecular pathogenesis of Spinocerebellar ataxia type 1 disease. Molecules and Cells. 27(6): 621-627. IF : 2.0 *Corresponding author.
 
24. Seok JongHong, Hyun Jin Choi, Sunghoi Hong,Youngbum Huh, Han Chae and Kwang-Soo Kim. 2008(September). Transcription factorGATA3 regulates the transcriptionalactivity dopamine-β hydroxylase byinteracting with Sp1 and AP4.NeurochemicalResearch.33(9):1821-1831.  IF : 2.3
 
23. Sunghoi Hong*,Soyoen Lee*, and Seongman Kang. 2008 (August 8).Theubiquitin-conjugating enzyme UbcH6 regulates the transcriptionalrepressionactivity of the SCA1 gene product ataxin-1. Biochemicaland Biophysical Research Communication (BBRC).372(4):735-740. IF : 2.8
*Both authors equally contributedto thiswork.
 
22. Sunghoi Hong,Soyoen Lee, Ssang-Goo Choand Seongman Kang. 2008 (June 27).UbcH6 interacts and ubiquitinates the SCA1 geneproduct ataxin-1. Biochemical andBiophysical ResearchCommunication (BBRC). 371(2):256-260. IF: 2.8
 
21. Seok JongHong, Han Chae, Thomas Lardaro, SunghoiHong and Kwang-Soo Kim. 2008 (April11 ). Trim11 increasesexpression of dopamine-β hydroxylase gene by interactingwith Phox2b. Biochemical and BiophysicalResearchCommunication (BBRC). 368(3):650-655. IF: 2.8
 
20. Dongwon Choi,Sun-Joo Lee, Sunghoi Hong, Ik-HwanKim, and Seongman Kang. 2008 (March13). Prohibitin interacts with RNF2 andregulates E2F1 function via dualpathways. Oncogene. 27(12):1716-1725.IF : 7.2
 
19. Sunghoi Hong, UnJung Kang, Ole Isacsonand Kwang-Soo Kim 2008(January).Neural precursors derived from human embryonic stem cells maintainlong-termproliferation without losing the potential to differentiate into allthreeneural lineages, including dopaminergic neurons. Journal of Neurochemistry. 104(2):316-324. IF : 4.6
 
18. MilesCunningham, Rachael Donalds, William A. CarlezonJr., Sunghoi Hong, Dae-Sung Kim,Dong-Wook Kim and Kwang-Soo Kim. 2007(Oct 29). Antidepressant Effect ofStem Cell-Derived Monoaminergic Grafts. NeuroReport.18(16):1663-1667. IF : 2.2
 
17. Sunghoi Hong, Dong-Youn Hwang, SoonsangYoon, Ali Ramezani, Robert G.Hawley, Ole Isacson and Kwang-Soo Kim 2007 (September). Functional analysisofvarious promoters in lentiviral vectors at different stages of in vitro differentiation of mouseembryonicstem cells. Molecular Therapy. 15(9):1630-1639.IF : 6.0 (This article was highlighted in “Biotechniques” 43:547,2007)
 
16. Eva Hedlund,Jan Pruszak, Angel Viñuela, Andrew Ferree, SunghoiHong, Ole Isacson and Kwang-SooKim. 2007(May). Selection ofembryonic stem cells-derived enhanced green fluorescenceprotein-positivedopamine neurons using the tyrosine hydroxylase promoter isconfounded byreporter gene expression in immature cell populations. Stem Cells. 25(5):1126-1135. IF: 7.7
 
15. Seok-JongHong, Youngbum Huh, Han Chae, SunghoiHong, Thomas Lardaro andKwang-Soo Kim. 2006(August). GATA3 regulatesthe transcriptional activity of tyrosine hydroxylaseby interacting with CREB. Journal ofNeurochemistry. 98(3):773-81.IF :4.5
 
14.Younjae Park, SunghoiHong, Sung-Jo Kim, and SeoungmanKang, 2005.Proteasome Function isInhibited by Polyglutamine-expanded Ataxin-1, SCA1 geneproduct. Molecules and Cells. 19(1),23-30. IF : 2.0 
 
13. Sung-Jo Kim,Tae-soo Kim, Sunghoi Hong, HyangshukRhim, Ick Young Kim, and Seongman Kang. 2003(September). Oxidative stimuliaffect polyglutamine aggregation and cell deathin human mutantataxin-1-expressing cells. NeuroscienceLetters.348(1): 21-24. IF : 2.1
 
12. Sung-Jo Kim,Tae-soo Kim, Ick Young Kim, Sunghoi Hong,Hyangshuk Rhim, andSeongman Kang. 2003(August). Polyglutamine-expandedataxin-1recruitsCu/Zn-superoxide dismutase into the nucleus of HeLa cells. Biochemical and Biophysical ResearchCommunication (BBRC). 307(3):660-665. IF: 2.8
 
11.Sunghoi Hong, Sojeong Ka, SungjoKim,Youngjae Park and Seongman Kang. 2003(May).p80coilin, a coiled body-specific protein, interacts with ataxin-1, the SCA1geneproduct. Biochimica et BiophysicaActa(BBA) -Molecular Basis of Disease 1638(1): 35-42. IF : 4.0
 
10.Sunghoi Hong,Sung-Jo Kim, Sojeong Ka, Inho Choi, and Seongman Kang. 2002(June). USP7, ubiquitin-specificprotease 7, interacts withataxin-1, SCA1 gene products. Molecularand Cellular Neuroscience (MCN)20(2): 298-306. IF :4.0
 
9. Kyung-OkLee,Jeong-Hoi Hoe and Sung-Hoi Hong.1998. A study of geneticpolymorphismsof new HLS genes, TAP1 and TAP2. Korean J. Immunol.Vol. 20 (1) 69-73. 
 
8. Kyung-Ok Lee, Sung-HoiHong,Min-Jung Kim, Taek-Kyu Park, Yoon-Jung Kim and Kyu-Pum Lee. 1997. Molecular Analysis of HLA-CPolymeraseChain Reaction-Sequence Specific Primers. J. Biochem. Mol. Biol.Vol. 30(1) 26-32. 
 
7. Kyung-OkLee,Jeong-Hoi Hoe, Hye-Jin Kim, Eun-Mi Lee, Sung-Hoi Hong and Yoon-JungKim 1997. Determination ofHLA-A*02Alleles Using Nested PCR-SSP in Korean Population. Korean J Biol Sci1:129-134.
 
6. Kyung-Ok Lee, Sung-HoiHong,Moon-Ju Oh, Kyung-In Kim and Min-Jung Kim. 1996.HLA-B27 DNA Typing using Group Specific Polymerase ChainReaction. Korean J.Biomed. Lab. Sci. vol. 2 (2). 223-229.
 
5. Sung-HoiHong,Kyung-Ok Lee, Yoon-Jung Kim and Kyu-Pum Lee. 1996. Analysis of Genetic Polymorphisms of the HLA-DPB1 LocusUsingPCR-RFLP in a Korean Population. Korean J. Genetics 18(4): 265-273.IF : 0.4
 
4. Kyung-Ok Lee, Sung-HoiHong,Jong-Hee Choo, Young-Suk Park, Yoon-Jung Kim, and Kyu-Pum Lee. 1996. HLA-A Genotyping UsingPolymeraseChain Reaction-Sequence Specific Primers: A Comparative Study withSerologicalTyping. Korean J. Genetics 18(4): 285-294. IF : 0.4
 
3. HongSH, Shin JS, Jeung JU, Ok SH. 1996. Molecularcloning and nucleotide sequencing of a DNA cloneencoding arginine decarboxylasein rice (Oryza sativa L.). Agri.Chem. Biotech. 39(2):112-117. 
 
2. Sohn JY,Bahn SC, Shin JS, Hong SH. 1996. Distribution offree sugars in the various portions ofwatermelon (Citrullus vulgaris L.)and muskmelon (Cucumis melovar. reticulatus Naud.). Agri.Chem. Biotech. 39(3):200-205. 
 
1. Shin JS,Jeung JU, Hong SH. 1994. Role of plantpolyamine and its metabolic regulation. NaturalResources and EnvironmentResearch 2:1-11. 
 
 
 

Recent POSTERor ORAL PRESENTATION (year/meeting/place/title)

27. 2017/ The Genetics Society of Korea / Seoul, Korea / transplantation of ESC-defived spinal GABAergic neural precusor cells attenuates spinal cord injury neuropathic pain.

26. 2017/ The Genetics Society of Korea / Seoul, Korea / direct conversion of fibroblast into neural stem cells by small molecules

25. 2017/ The Genetics Society of Korea / Seoul, Korea / Neural stem cell-derivates restore hair regrowth by activation of the hair follicle niche through a counterbalanced regulation of TGF-beta and BMP signaling.

24. 2017/ The Genetics Society of Korea / Seoul, Korea / spatio-tempotally controlled transfection by recisive injection into a single cell.

23. 2017/ The Genetics Society of Korea / Seoul, Korea / Gentic Stability of induced pluripotent stem cells(iPSCs) treated with small moleccules. 

22. 2017/ Korea Society for Stem Cell Research / Seoul, Korea / Spatio-temporally controlled transfection by quantitative injection into a single cell.  

21. 2016/ Korea Society for Stem Cell Research / Seoul, Korea / Intrathecal Transplantation of Pluripotent Stem Cell-Derived Spinal GABAergic Neural Precursor Cells Attenuates Neuropathic Pain in a Spinal Cord Injury Rat Model.

20. 2016/ Korea Society for Stem Cell Research / Seoul, Korea / Generation of induced pluripotent stem cells with genetic stability by small molecules.
 
19. 2015/ InternationalSociety for Stem Cell Research / Stockholm, Sweden / Molecular and cellular analysis during in vitro GABAergicdifferentiation of iPSC generation from Huntington’s disease patient.
 
18. 2015/ InternationalSociety for Stem Cell Research / Stockholm, Sweden / Intrathecal Transplantation of Embryonic StemCell-Derived Spinal GABAergic Neural Precursor Cells Attenuates NeuropathicPain in a Spinal Cord Injury Rat Model..
 
17. 2015/ InternationalSociety for Stem Cell Research / Stockholm, Sweden / Molecular and cellular characterization of induced cancer stemcell-like cells. 
 
16. 2015/ InternationalSociety for Stem Cell Research / Stockholm, Sweden / Generation of induced pluripotent stem cellswithout genetic defects by small molecules.
 
15. 2013/ Korean Tissue EngineeringandRegneratiive Medicine Society / Seoul, Korea / Combinationof a histone deacetylase inhibitor A and BMP2promotes bone formation in rabbitcalcarial bone defects . 
 
14. 2013/ Society of Cosmetic Scientists ofKorea/ Seoul, Korea / Neural stem cell-conditioned medium inhibits melaninproduction (Oral).
 
13. 2013/ The Korean Society for MolecularandCellular Biology / Seoul, Korea Neural stem cells recuce proliferation andteratoma of embryonicstem cells.
 
12. . 2013/ International Society for StemCellResearch / Boston,, USA / Efficient differentiation of dopaminergic(DA) neurons fromchemical-treated iPSCs.
 
11. 2013/ International Society for StemCellResearch / Boston,, USA / Efficient generation of dopaminergic neuronsthrough directregulation of tyrosine hydroxylase and neurogenin 2 by pitx3 inembryonic stemcell-derived neural precursors.
 
10. 2013/ International Society for StemCellResearch / Boston,, USA / Neural stem cell-extracts promote hair growthin vivo and increasegrowth factors in vitro.
 
9. 2013/ International Society for StemCellResearch / Boston,, USA / CONVERSION OF HUMAN IMMORTALIZED CELLS TOCANCER STEM CELL-LIKECELLS. 
 
8. 2013/ International Society for StemCellResearch / Boston,, USA / DISEASE-SPECIFIC INDUCED PLURIPOTENT STEMCELLS AS A USEFUL STEMCELL MODEL FOR HUNTINGTON’S DISEASE.
 
7. 2013/ The Korean Society for BiochemistryandMolecular Biology / Seoul, Korea / Selective delivery of nuclear reprogrammingfactors intosingle somatic cell via nanotube-based nanotechnology.
 
6. 2013/ The Korean Society for BiochemistryandMolecular Biology / Seoul, Korea / Rapid and efficient reprogramming of mouseadultfibroblast to induced pluripotent stem cells by using small molecules. 
 
5. 2012/ International Society for StemCellResearch / Yokohama, Japan / Neural stem cell derived conditionedmediumsuppresses melanogenesis through inhibition of WNT/β-catenin signalingpathway.
 
4. 2012/ International Society for StemCellResearch / Yokohama, Japan / Chemicals enhance stemness of induced pluripotentstemcells.
 
3. 2012/ International Society for StemCellResearch / Yokohama, Japan / Direct conversion of somatic cellsintoneurallineages.
 
2. 2011/ The Korean Society for MolecularandCellular Biology / Seoul, Korea / Efficient differentiation of humaninducedpluripotent stem cells into dopaminergic neuronal cells. 
 
1. 2011/ The Korean Society for MolecularandCellular Biology / Seoul, Korea / SUMO-1 interacts with mutant ataxin-1andcolocalizes to its aggregates in Purkinje cells of SCA1 transgenic mice.
 
 
 

BOOKS 

4. 캠벨 생명과학 (10판) 대표역자 전상학 등(전체 20여명-홍성회 포함). 2016년 8월. ㈜바이오사이언스출판. ISBN : 978-89-6824-058-4 93470
 
3.ATAXIA:Causes, Symptoms and Treatment.Sunghoi Hong as editor. 2012 August. NovaScience Publishers, Inc. in New York. Chapter11. Stem cell replacementtherapy as a potential treatment for SCA1 disease.Sunghoi Hong* and Seongman Kang.ISBN : 978-1-61942-867-6. (Chapters in this bookwere edited by SunghoiHong as an editor )
 
2.병리학 (개정판). 홍성회등 (전체 21명).2011년 3월. 도서출판고려의학. ISBN :978-89-7043-801-6
 
1.조직학 (개정판). 홍성회등 (전체 21명).2010년 8월. 도서출판 고려의학.ISBN : 978-89-7043-774-3
 
 
 

PATENT LIST  
 
[국내특허]

 

14. GCC2 억제제를 유효성분으로 포함하는 암 예방 또는 치료용 조성물. 출원번호:10-2023-0137922. 발명자: 홍성회, 박지호, 신건섭

13. Lin28A 억제제를 유효성분으로 포함하는 헌팅턴병 지연 또 는 치료용 조성물. 출원번호:10-2023-0137927 . 발명자:홍성회, 신정모

12. 인공지능을 이용한 세포 판별 방법 및 장치. 출원번호: 제 10-2022-0135609 . 발명자:홍성회 김민재

11. 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물. 등록번호 : 제10-1655383 호. 발명자 : 홍성회, 박항수, 황인식, 최경아, 정혜선. 등록
 
10. 소분자 화합물을 이용한 인간 섬유아세포를 신경줄기세포로 직접전환하는 방법. 출원번호: 10-2015-0051993. 발명자 :홍성회, 최경아, 황인식. 출원
 
9. 신경줄기세포 배양액을 유효성분으로 함유하는 기형종형성 및 성장억제용 조성물. 등록번호: 10-1615298. 발명자 : 홍성회, 박한결, 정혜선. 등록 (2016년 4월 19일)
 
8. 유전물질의 단일세포 내 정량적 전달방법. 등록번호: 10-1599496. 발명자 : 최연호, 홍성회, 권효성, 박항수. 등록(2016년 2월 25일)
 
7. 신경특이인자 및 신경영양인자를 이용하여 체세포로부터 신경전구세포, 신경세포, 희소돌기아교세포, 별아교세포 또는 도파민 신경세포를 유도하는 방법. 등록번호: 제10-1548318 호.  발명자 : 홍성회, 오승익, 박항수. 등록 (2015년 8월 24일)
 
6. 불멸화된 세포주로부터 암 줄기세포주를 제조하는 방법. 등록번호: 제10-1583019호.  발명자 : 홍성회, 오승익, 박항수, 정혜선. 등록(2015년 12월 30일) 
 
5. 염색체 안전성을 유지시키는 소분자성 화합물을 포함하는만능성 줄기세포 배양조성물과 이를 이용한 배양방법. 출원번호: 10-2013-0089205.  발명자 : 홍성회, 박항수, 황인식, 최경아. 출원
 
4.외부유전자의 도입 없이 중간엽 줄기세포로부터 신경줄기세포를 생산하는 방법.특허등록번호10-1285440. 발명자: 홍성회, 오승익.등록 (2013년7월5일)
 
3. 신경줄기세포 추출물을함유하는 발모촉진 또는 탈모방지용 조성물 및 이의 제조방법. 등록번호: 10-1597606.  발명자 : 홍성회, 황인식, 최경아. 등록 (2016년 2월 19일) 
 
2. 신경줄기세포 배양액또는 신경줄기세포 추출물을 유효성분으로 함유하는 미백용 화장료 조성물 및 이의 제조방법. 등록번호: 제 10-1548317 호.  발명자: 홍성회, 황인식, 오승익, 박항수. 등록(2015년 8월 24일) 
 
1.아탁신-1 유전자 또는아탁신-1 단백질을 유효성분으로포함하는 항암용조성물 및그를 이용한항암제 스크리닝방법. 특허번호 10-0982909. 발명자; 강성만,이소연, 홍성회. 등록
 
 

[국외특허]

9. COMPOSITION FOR MAINTAINING CHROMOSOMAL STABILITY OF PLURIPOTENT STEM CELLS, CONTAINING SMALL-MOLECULE COMPOUND. 출원번호 : E.P.O 14832827.1. 발명자: 홍성회, 박항수, 최경아, 황인식. 출원
 
8. COMPOSITION FOR MAINTAINING CHROMOSOMAL STABILITY OF PLURIPOTENT STEM CELLS, CONTAINING SMALL-MOLECULE COMPOUND. 출원번호 : JP (PCT/KR2014/006642). 발명자: 홍성회, 박항수, 최경아, 황인식. 출원
 
7. COMPOSITION FOR MAINTAINING CHROMOSOMAL STABILITY OF PLURIPOTENT STEM CELLS, CONTAINING SMALL-MOLECULE COMPOUND. 출원번호 : U.S.A. 14/906,547. 발명자: 홍성회, 박항수, 최경아, 황인식. 등록
 
6. A chromosome stabilityincreasingcomposition comprising small molecules for pluripotent stem cell, andtheprocess for cell culture. 출원번호 : PCT/KR2014/006642. 발명자: 홍성회, 박항수, 최경아, 황인식. 출원
 
5. Composition for promoting growthof hairor preventing loss of hair comprising neural stem cell extract, andprocess forproducing the same. CHINA 출원번호 : 1100605076.4. 발명자: 홍성회, 황인식, 최경아. 출원

4. Composition for promoting growthof hairor preventing loss of hair comprising neural stem cell extract, andprocess forproducing the same. JAPAN 출원번호 : IP-2015-0107. 발명자: 홍성회, 황인식, 최경아. 출원

3. Composition for promoting growthof hairor preventing loss of hair comprising neural stem cell extract, andprocess forproducing the same. U.S.A. 출원번호 : 14/785,255. 발명자: 홍성회, 황인식, 최경아. 등록

2. Composition for promoting growthof hairor preventing loss of hair comprising neural stem cell extract, andprocess forproducing the same. 출원번호 : PCT/KR2014/003324.발명자: 홍성회, 황인식, 최경아. 출원
 
1. Method for generation of cancerstemcells from immortalized cell lines. U.S.A. 출원번호: 14/222,697.발명자: 홍성회, 오승익, 박항수. 등록
 
 

[기술이전] 
3 소분자 화합물을 이용한 인간 섬유아세포를 신경줄기세포로 직접 전환하는 방법: 2019. 기술실시대상국가: 대한민국. 기술료계약금액: 15억원. 기술실시회사 : 인스템케어(주)


2. 신경줄기세포 배양액 또는 추출물을 유효성분으로 함유하는 미백용 화장료 미 발모촉진 또는 탈모방지용 조성물 및 이의 제조방법:2017. 기술실시대상국가: 대한민국. 기술료계약금액 : 2억원. 기술실시회사 : 미래CT(대표 박한규)

1. 염색체 안전성을 유지시키는 소분자성 화합물을 포함하는 만능성 줄기세포 배양조성물과이를 이용한 배양방법. 최초계약실시연도: 2014. 기술실시대상국가: 대한민국. 기술료계약금액 : 3천만원. 기술실시회사 : ㈜바이오 써포트 (대표 강호경).전용실시권. 
 
 

CONTRIBUTIONSAS PAPER REVIEWER(Year/Journal/Authors/Title)
 
2015 / Stem Cells and Development/ Piscopo EC V et al. ..PorzioUd. / Overexpression transcription factors Mach1 and Nurr1 increasesdopaminergic differentiation of mouse neural stem progenitor cells.
 
2015 / Nature Protocol / Fjodorova M. et al. ..Li M. / Robustinduction of DARPP32 expressing GABAergic striatal neurons from humanpluripotent stem cells.
 
2015 / PLOS one / Dingle YTL et al. …Zervas M. ../Quantitative analysis of dopamine neuron subtypes generated from mouseembryonic stem cells.
 
2015 / Nature Protocol /Richner M. et al. … Yoo A.S. /MicroRNA-based conversion of human fibroblasts into striatal medium spinyneurons.
 
2014/ Cellular andMolecular Neurobiology / Oyama H et al./ Long-term culture of human induced stem cell-derived forebrainneuronaggregates on collagen gel.
 
2014/ Stem CellReviews and Reports / Kim HS et al./ PSA-NCAM+neural precursor cells (NPC) exert theirneuro-protective effects throughanti-reactive gliosis and pro-angiogenesis ina rat stroke model.
 
2014 / BiotechnologyJournal / Jang J et al. / Agroundbreaking approach in modelingpediatric neurological disorders: inducedpluripotent stem cells. 
 
2014 / PLOS ONE/Hartman ML et al. / Geneexpression profiling identifiesDickkopf-1(DKK1) and microphthalmia-associatedtranscription factor (MITF) asregulators of melanoma phenotypic heterogeneity.
 
2012 / TSWJ /Taniuchi F et al. / Transcriptional regulation offucosyltransferase 1 geneexpression in colon cancer cells.
 
2012 / TSWJ / EstayF et al. / Comparison of oogenesis and sex steroidprofiles between twice- andonce-annual spawning rainbow trout females (Oncorhynchusmykiss).
 
2012 / TSWJ / AbdelAziz MT et al. / Heme oxygenase effect on MSCs actionin experimental Alzheimer’sdisease.
 
2011 /Cytokine / Kim B et al. /Differentiation of human labia minora dermis-derivedfibroblasts intoinsulin-producing cells. 
 
2011 / Tissueengineering and regeneration / Kim HT et al. / Thefeeder-free culture of humanembryonic stem cells and induced pluripotent stemcells in the presence ofhistone deacetylase inhibitors. 
 
2010 / Stem Cell Reviews and Reports / Kim DS et al. /Robust enhancement of neuraldifferentiationfrom human ES and iPScells regardlessof their innate difference in differentiation propensity.
 
2009 / EMM / Lim JYet al. / Microporation for efficient gene deliveryinto human umbilical cordblood-derived mesenchymal cells and multiple stem celltraits.

Publications
Books
Patent
technology transfer
bottom of page